Chromosome screening
PGT-A screens embryos for missing or extra chromosomes before transfer.
Preimplantation Genetic Testing
Preimplantation genetic testing (PGT) in Baner, Pune
Advanced embryo genetic screening during IVF to identify genetic and chromosomal abnormalities before embryo transfer.
Embryo genetic screeningPGT is coordinated within an IVF or ICSI cycle before embryo transfer.
Inherited condition support
PGT-M may be used when carrier status or family history is part of the clinical picture.
Informed IVF planning
Genetic results help guide embryo transfer discussions with the fertility team.
Overview
Accurate embryo screening before IVF transfer
Achieve healthier pregnancies with accurate embryo genetic screening in Baner, Pune at Nakshatra Clinic. Our advanced preimplantation genetic testing (PGT) identifies genetic and chromosomal abnormalities in embryos before IVF transfer. By selecting only the healthiest embryos, this advanced fertility diagnostic test in Baner, Pune helps reduce the risk of miscarriage, implantation failure, and inherited disorders.
Types Of PGT
Types of preimplantation genetic testing
The main types of PGT and what each test may screen for during IVF planning.
PGT-A (Aneuploidy)
This test screens embryos for chromosomal abnormalities. Healthy embryos should contain 23 pairs of chromosomes, one from the egg and one from the sperm.
PGT-M (Monogenic Disorders)
Targets specific inherited diseases when one or both partners are carriers or there is a family history. It supports transferring unaffected embryos and breaking the chain of transmission.
PGT-SR (Structural Rearrangements)
Used when structural chromosome rearrangements are part of the evaluation, helping guide embryo transfer planning.
- Family history of genetic conditions.
- Carrier of an X-linked or autosomal recessive disease.
Benefits And Limits
What PGT can and cannot tell you
What PGT can help identify before embryo transfer, along with its limitations.
Supports embryo selection
PGT helps the team identify embryos with the desired genetic or chromosomal result before transfer.
Not a guarantee
PGT screens for known abnormalities, but other medical, environmental, or lifestyle factors can still influence pregnancy outcomes.
May need interpretation
Some embryos may have inconclusive or mosaic patterns, so genetic counseling before and after testing is important.
PGT Explained
PGT testing in Pune: how embryo testing works
A plain-language guide to preimplantation genetic testing within an IVF or ICSI cycle, and what to ask before deciding.
What PGT means
Preimplantation genetic testing (PGT) is embryo genetic testing: a small sample of cells from an embryo is analysed in the laboratory before transfer. It can only be done on embryos created through IVF or ICSI, and it is not needed by every IVF patient. Whether it is relevant depends on your history and your specialist's clinical assessment, and decisions follow applicable regulations.
PGT-A, in plain terms
PGT-A looks at the number of chromosomes in an embryo. Embryos with missing or extra chromosomes can be identified, which may be discussed for some patients, for example depending on age or previous history. It does not look for specific inherited conditions.
PGT-M, in plain terms
PGT-M looks for one specific inherited single-gene condition that is already known in the family, for example when both partners are carriers. The gene change is usually identified first through prior testing of the parents or relatives, so the lab knows what to look for.
PGT-SR, in plain terms
PGT-SR is considered when a parent carries a structural change in the chromosomes, such as a balanced translocation or inversion. It checks whether an embryo has an unbalanced result linked to that rearrangement, which may be associated with repeated miscarriage or difficulty conceiving.
The embryo testing journey
After egg collection and fertilisation, embryos are grown in the laboratory to the blastocyst stage. A few cells from the outer layer are carefully taken in an embryo biopsy and sent for analysis. The embryos are usually frozen while the results are awaited, and results are then discussed with you before any frozen embryo transfer is planned.
Counselling matters
Genetic counselling before testing helps you understand what a test can and cannot show, and is especially important for PGT-M and PGT-SR. After testing, a counselling discussion helps explain the results and the options that may follow.
Limits to keep in mind
No genetic test is perfect. Results can occasionally be inconclusive or show mosaic patterns, and a normal result cannot promise a pregnancy or a healthy baby. Your specialist may also discuss confirming a pregnancy with prenatal testing.
Questions to ask at your consultation
Is PGT relevant to my history, or can I proceed without it? Which type of PGT is being considered, and why? How are embryos biopsied and frozen? What might an inconclusive or mosaic result mean for me? Will I have genetic counselling before and after testing?
Consultation
PGT consultation in Baner–Balewadi, Pune
If you would like to discuss whether preimplantation genetic testing is relevant to your situation, you can book a consultation at Nakshatra IVF. Bring any previous test reports, carrier screening results or family history details so your specialist can review them with you.
FAQ
Frequently Asked Questions
Preimplantation Genetic Testing (PGT) is an advanced embryo screening technique performed during an IVF cycle to identify genetic or chromosomal abnormalities before embryo transfer. It ensures that only healthy embryos are selected for implantation, improving IVF success rates and reducing the risk of miscarriage or inherited genetic disorders. This test is especially helpful for couples facing infertility or repeated IVF failures.
The main benefits of Preimplantation Genetic Testing include higher IVF success and implantation rates, reduced chances of miscarriage, prevention of inherited genetic diseases, fewer IVF cycles needed to achieve pregnancy, and selection of the healthiest embryos for transfer.
The success rate of PGT with IVF depends on factors like maternal age, embryo quality, and lab expertise. On average, couples undergoing PGT experience implantation rates of 65-80%, compared to 40-50% without testing. Clinics with experienced embryologists and genetic counselors, such as Nakshatra Clinic in Baner, Pune, consistently achieve higher pregnancy success rates.
Though highly accurate (up to 98%), PGT is not 100% foolproof. Some embryos may yield inconclusive results or have mosaic patterns. Additionally, a small chance of false positive or false negative exists. Consulting a genetic counselor before and after the test helps interpret results correctly and plan next steps confidently.
PGT is usually scheduled during an IVF or ICSI cycle, right after fertilization and before embryo transfer. Your fertility team will plan the exact timeline based on your cycle stage and hormonal profile.
While PGT significantly reduces the risk of passing on genetic or chromosomal disorders, it cannot guarantee a completely healthy baby. It screens for known abnormalities, but other factors, such as environment or lifestyle, can still influence pregnancy outcomes.
No. PGT is an optional addition to IVF or ICSI and is not needed by every patient. Your fertility specialist may discuss it depending on your age, medical and family history, previous outcomes and applicable regulations.
Embryos are usually grown to the blastocyst stage, when a few cells from the outer layer, which later forms the placenta, are carefully removed by an embryologist. The embryos are then usually frozen while the biopsy sample is analysed, and results are reviewed with you before a transfer is planned.
PGT-A checks the number of chromosomes in an embryo. PGT-M looks for a specific inherited single-gene condition already known in the family. PGT-SR checks for unbalanced results linked to a structural chromosome rearrangement carried by a parent. Your specialist can explain which, if any, may be relevant.
Genetic counselling before testing is recommended, especially for PGT-M and PGT-SR, so you understand what the test can and cannot show. A discussion after the results helps explain them and the next steps.
Book A Consultation
Need guidance on PGT with IVF?
Book a consultation at Nakshatra Clinic in Baner, Pune to discuss preimplantation genetic testing, IVF or ICSI planning, and embryo transfer guidance.