Laser Assisted Hatching Treatment in Pune
What is Laser-assisted hatching?
By creating a hole in the zona pellucida membrane (the outermost layer of the embryo’s shell), a technique known as laser-assisted hatching aids in the hatching or breaking through of embryos during in vitro fertilization. This layer may become exceptionally thick and/or stiff as a result of the freezing and thawing processes, among other factors.
The greater the ease with which an embryo hatches, the higher the likelihood that the embryo will adhere to the uterine wall or implant in the uterus. The use of laser-assisted hatching may be essential in completing these key phases to successfully establish pregnancy in certain cases.
Everything You Need to Know About Laser Assisted Hatching
Procedure | Candidate | Advantages | Indications | FAQs
What is the procedure?
To remove the embryo, an embryologist must first create a tiny hole in the embryo’s shell using a microscope so that it may be removed. A few days after fertilization has occurred, the embryo has already begun to cleave, which is usually done three days after the procedure has been completed (divide).
In addition, it takes just a few seconds and has no harmful consequences for the growing fetus. If all goes according to plan, an embryo will be placed in the patient’s uterus where it will continue to grow.
In Vitro Fertilization
In vitro fertilization is a modern reproductive procedure. We use it to treat infertility and help couples in conceiving. During IVF, developed eggs are extracted from ovaries and fertilized by sperm in a laboratory.
In Vitro Maturation
In-vitro maturation, or IVM, is an assisted reproductive technology (ART). The original procedure of oocyte IVM has been accessible since the 1990s; however, doctors rarely use it due to IVF viewing better returns.
Laser Assisted Hatching
By creating a hole in the zona pellucida membrane (the outermost layer of the embryo’s shell), a technique known as laser-assisted hatching
IVF failure is the most common thing as unfortunately; IVF treatment cannot provide you success. An IVF failure can be the most frustrating thing ever for you and your partner.
Sperm Donation is the process where a male gender provides his sperm to another couple or person. The overall process of collecting and donating semen to a person or couple is sperm donation.
Repeated Implantation Failure
At the time of transferring embryos with the help of In Vitro Fertilization when the embryos fail to get transplanted, it can be then considered as the Implantation Failure.
Preimplantation Genetic Testing
A woman who faces infertility or recurrent pregnancy loss, that woman is chronic to the chromosomal abnormalities in the embryo.
Women’s ovaries produce gametes known as ova or ovum. These immature egg cells become mature ovum during a menstrual cycle.
Oligo Astheno Teratozoospermia
Oligo-Astheno-teratozoospermia (OAT) is a condition that leads to a low sperm count. This condition does not include anyone kind of disorder but can be divided into three disorders.
After you conceive a baby through IVF, you could uncover a circumstance that suggests more embryos than you are known. In such situations, you can either store them for the future or can discard them.
Sperm Freezing & Vitrification
Another name for sperm is spermatozoon which is in a plural form known as spermatozoa. This is a male reproductive cell, produced by the male gender animals.
Embryos Freezing & Vitrification
The embryo is defined as the early stage of development of a multicellular organism that is reproduced sexually. In simple terms, Embryo is an organism that has not totally developed and is in the previous stage of growth and differentiation.
Microsurgical Testicular Sperm Extraction commonly known as Micro-TESE is a surgical procedure that is performed to retrieve sperm from the male testicles seminiferous tubules.
Endometrial Receptivity Analysis
ERA or Endometrial Receptivity Analysis is a genetic test to evaluate endometrial lining. Only a developed endometrial lining accepts embryos and increases the implantation chances.
Who is assisted hatching recommended for?
However, although any patient may benefit from the laser-assisted hatching process, those who will gain the most from it are those who fulfill the following criteria:
- Have reached the age of 37 or above
- Increase the number of follicles produced
- Early in their cycle, they produce FSH (Follicle Stimulating Hormone)
- Have experienced failed IVF cycles
- Have a propensity for producing a thicker and/or tougher zona pellucida
12+ Years of Experience as
Sexologist and Infertility Specialist
12+ Years of Experience as
Sexologist and Infertility Specialist
Advantages of laser-assisted hatching
Several advantages of laser-assisted hatching are superior to those of other methods of assisted hatching (chemical and manual), including the following:
- The embryo is handled as little as possible.
- Control of the shell opening drilling is quick and precise.
- It’s mild and safe for the embryo, with no side effects.
- Broad patient accessibility and clinical advice are provided based on your specific circumstances.
Indications for LAH
The development of precise methods for manipulating embryos to increase fertility has been made possible by the invention of the laser. The use of laser-assisted hatching may help embryos that have previously failed to embed themselves in the uterine wall succeed this time.
In the case of embryo transfer, assisted hatching is utilized to assist the embryo in hatching from its protective outer shell, known as the zona pellucida, and to aid in the promotion of implantation in the uterine wall. Laser-assisted hatching (LAH) is a technique that removes the zona pellucida in extremely precise increments by using a highly concentrated infrared laser beam.
Before the availability of lasers in therapeutic settings, the only techniques available for assisting the hatching of human embryos in clinical settings were mechanical or chemical approaches. There is less handling of the embryo while using laser-aided hatching compared to the other assisted hatching techniques. Furthermore, since laser-assisted hatching is quicker than the other techniques, the embryo spends less time outside the incubator as a result of the procedure.
If you are having IVF, it does not automatically follow that you will be referred for LAH. According to experts, LAH may increase the chances of a successful pregnancy in certain kinds of couples. Your fertility specialist can decide whether LAH is a good fit for you after reviewing all of your medical records and infertility history with you.
In general, aided hatching may increase the likelihood of a pregnancy in the following circumstances.
- If you have had two or more unsuccessful IVF rounds, you may be eligible for a free consultation
- If you have a high FSH level, you should see your doctor
- There is a problem with the quality of your embryo
- When you are 37 years old or older
- Unexplained Infertility
Older women are more likely to develop eggs with a thick zona pellucida, or outer shell than younger women. Females who have a high amount of follicle-stimulating hormones are also affected by this issue (FSH). In such instances, the egg will not hatch and will not be able to connect to the womb. All of these infertility problems may benefit from the use of assisted hatching techniques.
Studies have also shown that frozen or thawed embryos have a hard zona pellucida, making it harder for them to hatch and implant in the uterus. Using laser-assisted hatching, a hole will be created in the outer shell, which will make it easier for the embryo to implant.
It is critical to understand that hatching is a natural process and that in the majority of IVF instances, the embryo implants in the womb after fertilization. It is possible that failure to hatch is an uncommon cause of infertility and that a more contemporary method is required. Additionally, it is important to speak with your reproductive doctor about the advantages and disadvantages of having LAH therapy in your particular situation. You should also consider the extra expense associated with this treatment.
FAQs – Laser Assisted Hatching
Does LAH increase the IVF success rate?
Successful implantation and pregnancy are more likely to occur with laser-assisted hatching than with traditional hatching methods. If you have had IVF failure, there is a possibility that you will be successful with assisted hatching. Consult with your fertility specialist to ensure that you make the best choice possible.
When is Laser-assisted hatching done in IVF?
Three days after fertilization, the eggs are harvested using laser aided hatching. Once the embryo has been successfully implanted, it may be cultivated until it reaches the blastocyst stage or transplanted into the uterus to attempt conception.
Can Laser-assisted hatching be done for frozen embryos?
Couples considering a frozen embryo transfer are advised to use laser-assisted hatching since studies have shown that frozen or thawed embryos have a harder zona pellucida, making it more difficult for them to develop into viable embryos.
Is Laser-assisted hatching suitable for everyone?
Laser-assisted hatching is usually suggested for women older than 37 years of age or for couples who have been unsuccessful in conceiving via traditional IVF treatment.
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Being a doctor myself, I was looking for a Gynaecologist who understands my concerns and solves it so easily that my non-doctor husband understands it well. Dr. Ramit is very compassionate and is really good at his skills. I would highly recommend him.
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Dr. Ramit Raosaheb Kamate
MBBS ,DNB, DGO, FRM (UK)
Dr. Ramit Kamate is a Reproductive Medicine Consultant and Sexologist with experience of 12+ years. He specialises in Sexual Medicine for male and female, Fertility Treatment, Pre and Post Delivery Care, Normal Vaginal Delivery (NVD), Tubectomy/Tubal Ligation, Natural Cycle IVF, MTP.
Dr. Ramit Kamate finished MBBS from B J Medical College, Pune. He pursued Masters’s In Reproductive Medicine from Hamilton University, UK & IBCME Dubai. Completed Fellowship in Cosmetic Gynaecology and Sexual Medicine from USA.
MBBS DGO DNB Gold Medalist
Fellow In Sexual Medicine (USA)
Fellow In Reproductive Medicine
Fellow In Cosmetic Gynecology (USA)
Fellow In Ultrasound And Laparoscopy
Fellow In Stem Cell Medicine
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