Women’s ovaries produce gametes known as ova or ovum. These immature egg cells become mature ovum during a menstrual cycle. The only difference between an egg and an ovum is that the ovum is the unfertilized female gamete whereas the egg is its fertilized form.
What is Ovum Donation in IVF?
Ovum donation in In Vitro Fertilization is a fertility therapy option for those who can not use their fertilized ovum. Moreover, it also means the intended mother will not be genetically related to the child. Also, if you use a sperm donor, the father will not be the biological parent. The process of donating an ovum or oocyte to another woman to help her conceive is a part of assisted reproductive technology or ART.
In Vitro Fertilization
In vitro fertilization is a modern reproductive procedure. We use it to treat infertility and help couples in conceiving. During IVF, developed eggs are extracted from ovaries and fertilized by sperm in a laboratory.
In Vitro Maturation
In-vitro maturation, or IVM, is an assisted reproductive technology (ART). The original procedure of oocyte IVM has been accessible since the 1990s; however, doctors rarely use it due to IVF viewing better returns.
Laser Assisted Hatching
By creating a hole in the zona pellucida membrane (the outermost layer of the embryo’s shell), a technique known as laser-assisted hatching
IVF failure is the most common thing as unfortunately; IVF treatment cannot provide you success. An IVF failure can be the most frustrating thing ever for you and your partner.
Sperm Donation is the process where a male gender provides his sperm to another couple or person. The overall process of collecting and donating semen to a person or couple is sperm donation.
Repeated Implantation Failure
At the time of transferring embryos with the help of In Vitro Fertilization when the embryos fail to get transplanted, it can be then considered as the Implantation Failure.
Preimplantation Genetic Testing
A woman who faces infertility or recurrent pregnancy loss, that woman is chronic to the chromosomal abnormalities in the embryo.
Women’s ovaries produce gametes known as ova or ovum. These immature egg cells become mature ovum during a menstrual cycle.
Oligo Astheno Teratozoospermia
Oligo-Astheno-teratozoospermia (OAT) is a condition that leads to a low sperm count. This condition does not include anyone kind of disorder but can be divided into three disorders.
After you conceive a baby through IVF, you could uncover a circumstance that suggests more embryos than you are known. In such situations, you can either store them for the future or can discard them.
Sperm Freezing & Vitrification
Another name for sperm is spermatozoon which is in a plural form known as spermatozoa. This is a male reproductive cell, produced by the male gender animals.
Embryos Freezing & Vitrification
The embryo is defined as the early stage of development of a multicellular organism that is reproduced sexually. In simple terms, Embryo is an organism that has not totally developed and is in the previous stage of growth and differentiation.
Microsurgical Testicular Sperm Extraction commonly known as Micro-TESE is a surgical procedure that is performed to retrieve sperm from the male testicles seminiferous tubules.
Endometrial Receptivity Analysis
ERA or Endometrial Receptivity Analysis is a genetic test to evaluate endometrial lining. Only a developed endometrial lining accepts embryos and increases the implantation chances.
When should you go for an Ovum Donation IVF?
The need for Ovum donation in IVF arises when the egg quality is poor due to advanced maternal age, ovarian failure, and congenital anomalies in the fetus. After the age of 37, the quality of the egg diminishes.
Here are a few reasons to consider Ovum Donation:
- Couples where a woman has poor quality or no egg but want a biological child.
- A woman without any ovary but has an intact uterus can consider going through Ovum donation.
- The woman with genetic factors but does not want to transfer that in her child.
- A woman over 42 can consider the above.
- A single male with a gestational carrier wants a child.
- Gay couples who want a baby.
- A woman with a history of cancer treatment.
- Women with continuous canceled or failed IVF treatment.
What is the Ovum Donation Process?
The procedure involves a doctor removing an egg or eggs from the donor, fertilizing them, and then transferring them into the woman to meet the embryos in the recipient’s uterus.
In Vitro Fertilization (IVF) is a common process of performing Ovum Donation. The doctors can freeze the embryos for further use or implementation in other women.
12+ Years of Experience as
Sexologist and Infertility Specialist
12+ Years of Experience as
Sexologist and Infertility Specialist
What is the Treatment for Ovum Donation?
The specialist at the fertility clinic will perform a high-quality selection process to find the perfect donor and will carefully start the legal procedures. Before beginning, several donors can use the medication to prevent the normal menstrual cycle.
After this, the surgeon, with the help of fertility drugs, will stimulate the donor’s ovaries to produce several eggs at a time, which is also known as hyper-stimulation.
Donors can perform self-administration by injecting the medicines under the skin or into the muscles. However, some adverse effects may potentially influence donors, such as ovarian hyper-stimulation syndrome (OHSS). The donor will also go through blood tests, including an ultrasound examination, to examine their reaction to the medications.
Time of Extraction
At the time of extraction, the donor will receive an injection to prepare herself for the procedure. The doctors will conduct transvaginal aspiration to extract the eggs from the donor’s ovary. The doctor will further insert an ultrasound probe inside the vagina. Next, he will remove the egg from the individual follicle with a needle. The whole procedure takes about 30 minutes to complete. Meanwhile, the doctor might give the donor some painkillers, sedatives or anaesthesia.
After performing Donation
Moreover, as this is not a major procedure, the donor might get a quick discharge and not stay in the clinic or hospital. But several women need few days of rest to recover from the transvaginal ovarian aspiration.
The doctor may also give some aftercare for the donor. In addition, in some cases, the egg donation process can provide a psychological impact. Thus, women can consult with a psychotherapist after the procedure to get relief from these situations.
Risks and side effects
The risks associated with egg donation are minimal. The methods and drugs used by egg donors are the same as those used by women who use their eggs in IVF, and they pose the same risk. During the recovery phase, anaesthesia entails a low risk, although there are not many consequences.
When the doctor puts the needle into the ovary, some women bleed. Damage to the colon, bladder or adjacent blood arteries may occur in rare situations. An injury or significant bleeding, on the other hand, is improbable.
Infection might even arise after the removal of eggs. The doctor may give antibiotics to prevent this. The medications used to induce ovulation in egg donors can sometimes cause mild, moderate, or severe OHSS. Always seek medical advice.
Symptoms that may need hospitalization in severe instances include:
- Breathing problems
- Fast gaining of weight
- Stomach ache
Criteria for the egg donor
There may be various conditions in which a woman can provide her eggs. These variables improve the chances of a healthy pregnancy and lower the risk of congenital issues.
Donors are typically between the ages of 21 and 35. Women in this age range are more likely to respond well to fertility medications and have higher egg quality and quantity.
Infections such as HIV and hepatitis C should not be present in donors. They should also be free of hereditary disorders, such as individuals who have the cystic fibrosis gene.
If a woman is at high risk of contracting HIV or other diseases, she can not donate. A person may also be unable to donate eggs if they can not give a thorough family medical history.
Some organizations offer preference to women who have already donated eggs or given birth.
How to choose an ovarian donor?
To find an ovum donor, a person should consult with the doctor in detail. Some of the sources from where you can find a donor might include the following:
- Avail information from the friend or the family members.
- You can ask or talk with another infertile couple who are willing to share their donors’ details.
- Eggs banks are great options to choose from if you are new.
- Several agencies can provide you required ovum donor.
- Fertility clinics offering IVF treatment are also a good option to search.
You can meet the donor depending on the contract you have signed, or there may not be a contract between you and your donor as well. While choosing, you should avail information about her as well. You should check their health and physical condition. As this is a matter of emotion between the donor and the recipient, everyone should be careful.
Explain the success rate for Ovum Donation?
According to the Center for Disease Control, 55.9% for fresh embryo transfer and 40.2% for frozen embryo transfer in the live birth rate for donor ovum IVF. This report is generated by performing national research in 2013. In some cases, the success rate might be lower, including sharing ovum with another infertile couple. While choosing the same family member as a donor can also lead to a lower success rate.
What is the cost of Ovum Donation?
The overall procedure of Ovum Donation is a little bit expensive. On average, the cost can be anything from $20,000 to $35,000 per cycle. Moreover, it depends on the source and the agency, including commercial egg donor agencies, recruit, screen, and match healthy donors with couples and individuals.
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Being a doctor myself, I was looking for a Gynaecologist who understands my concerns and solves it so easily that my non-doctor husband understands it well. Dr. Ramit is very compassionate and is really good at his skills. I would highly recommend him.
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Dr. Ramit Raosaheb Kamate
MBBS ,DNB, DGO, FRM (UK)
Dr. Ramit Kamate is a Reproductive Medicine Consultant and Sexologist with experience of 12+ years. He specialises in Sexual Medicine for male and female, Fertility Treatment, Pre and Post Delivery Care, Normal Vaginal Delivery (NVD), Tubectomy/Tubal Ligation, Natural Cycle IVF, MTP.
Dr. Ramit Kamate finished MBBS from B J Medical College, Pune. He pursued Masters’s In Reproductive Medicine from Hamilton University, UK & IBCME Dubai. Completed Fellowship in Cosmetic Gynaecology and Sexual Medicine from USA.
MBBS DGO DNB Gold Medalist
Fellow In Sexual Medicine (USA)
Fellow In Reproductive Medicine
Fellow In Cosmetic Gynecology (USA)
Fellow In Ultrasound And Laparoscopy
Fellow In Stem Cell Medicine
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