Chorionic Villus Sampling in Pune

Chorionic villus sampling in pune

What is Chorionic Villus Sampling?

A CVS test, or chorionic villus sampling, collects placental tissue and tests it for chromosomal abnormalities and genetic diseases including Down syndrome. The placenta is a uterine organ that delivers nutrients and blood to the infant. It is to blame.

They are tiny finger-like extensions of placental tissue that transport the fetus’ genetic material. The availability of lab testing at the time of surgery may allow you to be checked for further genetic illnesses and anomalies.

Everything You Need to Know About Chorionic Villus Sampling

Why it’s Done | Procedure Reasons | Risks | Expect During & After | Results | FAQs

Why it’s done

Samples of your baby’s chorionic villus may provide information about the genetic make-up of your child. Pregnancy management or your willingness to continue your pregnancy may be jeopardized if you choose not to undergo a chorionic villus sample.

Chorionic villus sampling, like other prenatal diagnostic procedures like amniocentesis, is often performed between weeks 11 and 14 of pregnancy.

If any of the following apply, you should think about chorionic villus sampling:

  • You had a positive prenatal screening test. A screening test’s results may indicate the need for additional testing, such as a chorionic villus sample, to determine the presence or absence of a condition.
  • There was a chromosomal problem in a prior pregnancy that you need to know about. Previous pregnancies with Down syndrome or other chromosomal disorders may put the current pregnancy at risk as well.
  • There is a chance that you are above the age of 35. When a woman is 35 or older, her baby is more likely to be born with a chromosomal abnormality like Down syndrome.
  • Your family has a genetic condition, or you or your spouse are a known carrier. While chorionic villus sampling is most often used to diagnose Down syndrome, it may also detect other genetic illnesses such as Tay-Sachs and cystic fibrosis.

Certain birth abnormalities, such as neural tube defects, cannot be detected via chorionic villus sampling. An ultrasound or genetic amniocentesis may be suggested instead of neural tube abnormalities are a concern.

You may be advised to avoid transcervical chorionic villus sampling, which is performed through the vaginal canal if you have the following conditions:

  • Herpes is an example of an active cervical or vaginal infection
  • Two-week history of vaginal bleeding or spotting
  • Having a uterus tilted or having noncancerous growths in your cervix or the bottom portion of your uterus blocks access to your placenta

Transabdominal chorionic villus sampling, which involves taking a sample from the uterus via the abdominal wall, should only be performed if:

  • When you’re pregnant, the placenta attaches to the rear of the uterus.

Related Conditions

Reasons for the procedure

In the first trimester of pregnancy, a chorionic villus sample may be utilized for genetic and chromosomal testing. Here are a few reasons why a woman might choose to have CVS:

  • There is a history of genetic illness, chromosomal abnormalities, or metabolic disorders in the patient’s immediate family.
  • Mothers above the age of 35 at the time of delivery
  • Chances of contracting a hereditary illness that is exclusive to women
  • Ultrasounds performed in the past with potentially problematic or abnormal results
  • Unusual results from a test using cell-free DNA

Your doctor may suggest a chorionic villus sample for various reasons.

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Risks of the procedure

There are many hazards associated with chorionic villus sampling, including the following:

  • Miscarriage: Chorionic villus sampling has a 0.22 percent chance of miscarriage.Rh sensitization: During chorionic villus sampling, some infant blood cells may reach your bloodstream. If you have Rh-negative blood and haven’t developed antibodies against Rh-positive blood, you’ll be injected with Rh immune globulin following your chorionic villus sample.
  • Stop producing Rh antibodies, which may damage the baby’s red blood cells if they cross the placenta after birth. A blood test may show whether your body has begun generating antibodies.
  • Infection: A uterine infection may occur very infrequently as a result of chorionic villus sampling.

Chorionic villus sampling has been linked in the past to finger and toe malformations in babies. However, only if the operation is performed before week 10 of pregnancy does the danger seem to be significant.

What you can expect

As an outpatient procedure or at the doctor’s office, chorionic villus sampling is often used.

During the procedure

Your doctor will first conduct an ultrasound to establish your baby’s gestational age and placenta placement. Your abdomen will be examined when you are on a back exam. After putting a special gel on your tummy, your doctor will use an ultrasound transducer to locate your baby.

Using the ultrasound image as a guide, your doctor will take a tissue sample from the placenta while you are still. This may be done through your cervix (transcervical) or your abdominal wall (transabdominal).

  • Transabdominal chorionic villus sampling: After cleaning your abdomen with an antibiotic, your healthcare provider will inject a long, thin needle into your uterus. The needle may sting when it enters your skin and cramp once it reaches your uterus. The placenta tissue will be collected using a syringe, and the needle will be destroyed after collection.
  • Transcervical chorionic villus sampling: After cleaning your vagina and cervix, your doctor will use a speculum to open your vagina and insert a thin, hollow tube into your cervix. After the catheter reaches the placenta, gentle suction will retrieve a small tissue sample.

After the procedure

After the surgery, you may feel some little vaginal bleeding.

After the treatment, you may return to your regular activities. However, you may want to take a day off from sexual activity and intense exercise.

The tissue sample will be examined in the meanwhile at a laboratory. As a consequence, waiting times may vary widely depending on the lab’s level of complexity.

If any of the following apply to you, speak with your physician right away.

  • Fluid leaking from your vagina
  • Heavy bleeding
  • A fever
  • Contractions of the uterus



Your doctor or genetic counselor can explain your chorionic villus sample findings. When test findings are ambiguous, amniocentesis, another prenatal diagnostic procedure, is required.

A false-positive test occurs when a chorionic villus sample is positive although no illness is present. The chorionic villus sample cannot detect all birth abnormalities, including spina bifida and others.

Your kid may have a chromosomal or genetic issue that can’t be addressed if you take chorionic villus samples. During this tough time, seek help from your medical staff and loved ones.

FAQs – Chorionic Villus Sampling

1. How much does a chorionic villus sampling cost?

Where you obtain it and whether you have insurance determine the cost of CVS. Many insurance policies cover CVS but check with yours to be sure.

If you don’t have insurance or your plan doesn’t cover it, you’ll have to pay. Your doctor’s office can tell you how much CVS costs and what payment options are available.

2. Chorionic villus sampling vs. amniocentesis

Amniocentesis and Chorionic Villus Sampling are prenatal diagnostic techniques that detect fetal genetic disorders. These tests identify fetal genetic abnormalities. Doctors prescribe chorionic villus samples when the chance of genetic abnormalities is high, and amniocentesis when the risk is minimal. The chorionic villus test is somewhat riskier than amniocentesis. Also, chorionic villus testing may be done before amniocentesis.

A pregnant woman may consider chorionic villus sampling or amniocentesis if she has a high-risk Down syndrome screening test, had genetic defects in a previous pregnancy, has one or more relatives with genetic disorders, has an abnormal ultrasound scan, or wants to ensure her baby has no genetic defects.

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Being a doctor myself, I was looking for a Gynaecologist who understands my concerns and solves it so easily that my non-doctor husband understands it well. Dr. Ramit is very compassionate and is really good at his skills. I would highly recommend him.


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Doctor is very friendly & attentive. Listens to you gives you plenty of time. one stop solutions for all diagnostics. All the test samples are collected at clinic only, Dr. Ramit Kamte is very compassionate and is really good at his skills. I would highly recommend him.

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Dr. Ramit Raosaheb Kamate


Dr. Ramit Kamate is a Reproductive Medicine Consultant and Sexologist with experience of 12+ years. He specialises in Sexual Medicine for male and female, Fertility Treatment, Pre and Post Delivery Care, Normal Vaginal Delivery (NVD), Tubectomy/Tubal Ligation, Natural Cycle IVF, MTP.

Dr. Ramit Kamate finished MBBS from B J Medical College, Pune. He pursued Masters’s In Reproductive Medicine from Hamilton University, UK & IBCME Dubai. Completed Fellowship in Cosmetic Gynaecology and Sexual Medicine from USA.

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